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FKBP8 Antibody

ArtNr PRS-46-841-0.1mg
Hersteller ProSci
Menge 0.1 mg
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen ELISA
Specific against other
Host Goat
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias FKBP8, FK506 binding protein 8, 38kDa, FKBP38, FKBPr38, FK506 binding protein 8 (38kD), FK506-binding protein 8, FK506-binding protein 8 (38kD)
Lieferbar
Shipping
blue ice or RT
By Research Area
Signal Transduction , Apoptosis
Homology
Expected Species Reactivity based on sequence homology: Human, Mouse, Rat, Dog, Cow
Immunogen
The immunogen for this antibody is: C-KLEPSNKTIHAELSK
Applications
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Preliminary experiments gave an approx 28kDa band in Human Brain (Frontal Cortex) and Rat Brain lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 44.6kDa according to NP_036313.3. The 28kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Clonality
Polyclonal
Conjugate
Unconjugated
Buffer
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20°C. Minimize freezing and thawing.
Concentration
500 ug/mL
Storage Conditions
Aliquot and store at -20˚ C. Minimize freezing and thawing.
Related Products
Cat. No. 46-841P - FKBP8 Peptide
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications
None
Ncbi Official Symbol
FKBP8
Accession #
NP_036313.3
Protein Gi #
52630440
Ncbi Gene Id #
23770
Ncbi Official Symbol
FKBP8
Ncbi Official Full Name
FK506 binding protein 8, 38kDa
Ncbi Organism
Homo sapiens
Swissprot #
Q14318
Background References 1
Wang HQ, Nakaya Y, Du Z, Yamane T, Shirane M, Kudo T, Takeda M, Takebayashi K, Noda Y, Nakayama KI, Nishimura M. Interaction of presenilins with FKBP38 promotes apoptosis by reducing mitochondrial Bcl-2. Hum Mol Genet. 2005 Jul 1; 14(13):1889-902. Epub 2005 May 19.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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