ArtNr |
PRS-33-059-100ug |
Hersteller |
ProSci
|
Menge |
100 ug |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
WB |
Specific against |
Human |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Runt-related transcription factor 3, Acute myeloid leukemia 2 protein, Core-binding factor subunit alpha-3, CBF-alpha-3, Oncogene AML-2, Polyomavirus enhancer-binding protein 2 alpha C subunit, PEA2-alpha C, PEBP2-alpha C, SL3-3 enhancer factor 1 alpha C |
Lieferbar |
|
Shipping |
blue ice or RT |
By Research Area |
Other |
Immunogen |
A RUNX3 recombinant protein fragment was used as the immunogen for this antibody. |
Applications |
Western blot: 2-4 ug/ml
Provided assay concentrations are suggestions only, RUNX3 antibody titration may be required for optimal results. |
Purification |
Protein G Affinity Chromatography |
Clonality |
Monoclonal |
Clone |
RNX864 |
Isotype |
IgG1, kappa |
Conjugate |
Unconjugated |
Buffer |
PBS with 0.1 mg/ml BSA and 0.05% sodium azide |
Concentration |
0.5 mg/mL |
Storage Conditions |
Aliquot and Store at -20˚ C. Avoid freez-thaw cycles. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
RUNX3 |
Ncbi Gene Id # |
864 |
User Note |
Optimal dilutions for each application to be determined by the researcher |
Ncbi Official Symbol |
RUNX3 |
Ncbi Official Full Name |
Runt-related transcription factor 3 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q13761 |
Background |
The Runt family of transcription factors is involved in both normal cell development and carcinogenesis. Runt-related transcription factor 3 has been shown to be a tumor suppressor. Hypermethylation and mislocalization of the protein to the cytoplasm leads to low levels of RUNX3 and increased proliferation of breast and gastric tumor cells. |
1st Image Caption |
Western blot testing of human samples with RUNX3 antibody at 2 ug/ml. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.