Hersteller |
ProSci
|
Kategorie |
|
Typ |
Antibody Primary |
Specific against |
Mouse |
Applikationen |
WB, ELISA |
Menge |
0.1 mL |
Host |
Mouse |
ArtNr |
PRS-32-195-0.1mL |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Alias |
ASPL, RCC17, TUG, UBXD9, UBXN9, Alveolar soft part sarcoma chromosomal region candidate gene 1 proteinTUG, ASPL, ASPS, ASPCR1 |
Shipping |
blue ice or RT |
By Research Area |
Growth Factor |
Immunogen |
Ni-NTA purified truncated recombinant TUG expressed in E. Coli strain BL21 (DE3). |
Applications |
Western Blot:1:500 - 1:2, 000 ELISA:Propose dilution 1:10, 000. Determining optimal working dilutions by titration test. |
Purification |
Antibody is purified by protein A affinity chromatography and resuspended in PBS with 0.2%BSA, 0.09% sodium azide. |
Clonality |
Monoclonal |
Clone |
4A11A6G11 |
Isotype |
IgG1 |
Conjugate |
Unconjugated |
Buffer |
Purified antibody in PBS containing 0.03% sodium azide. |
Storage Conditions |
Mouse TUG monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
ASPSCR1 |
Accession # |
Q9BZE9 |
Protein Gi # |
74717746 |
Ncbi Gene Id # |
79058 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
ASPSCR1 |
Ncbi Official Full Name |
alveolar soft part sarcoma chromosome region, candidate 1 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q9BZE9 |
Background |
The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin. |
Background References 1 |
Nature 2003, 425:727 - 733. |
1st Image Caption |
Western blot analysis using Mouse TUG monoclonal antibody against NIH / 3T3 cell lysate. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.