MUC1 Antibody

Cancer

MUC1 antibody can be used for detection of MUC1 by ELISA at 1:312500. MUC1 antibody can be used for detection of MUC1 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.

22 kDa, 28 kDa, 28 kDa, 16 kDa, 17 kDa, 30 kDa

Polyclonal

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MUC1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

None

NP_001037855

4582

MUC1

Homo sapiens

MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.

Antibody used in IHC on Pig stomach at 1:500.

Antibody used in IHC on Human Kidney at 4.0-8.0 ug/ml.