ArtNr |
PRS-29-577-100ul |
Hersteller |
ProSci
|
Menge |
100 ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
WB, IHC, ELISA |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
MUC1, CD227, EMA, PEM, PUM, mucin, MCD, KL-6, MAM6, MCKD, PEMT, H23AG, MCKD1, MUC-1, ADMCKD, ADMCKD1, CA 15-3, MUC-1/X, MUC1/ZD, MUC-1/SEC |
Lieferbar |
|
Shipping |
blue ice or RT |
By Research Area |
Cancer |
Immunogen |
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MUC1. |
Applications |
MUC1 antibody can be used for detection of MUC1 by ELISA at 1:312500. MUC1 antibody can be used for detection of MUC1 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000. |
Positive Control 1 |
Cat. No. 1205 - Jurkat Cell Lysate |
Predicted Molecular Weight |
22 kDa, 28 kDa, 28 kDa, 16 kDa, 17 kDa, 30 kDa |
Purification |
Antibody is purified by protein A chromatography method. |
Clonality |
Polyclonal |
Conjugate |
Unconjugated |
Buffer |
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Concentration |
batch dependent |
Storage Conditions |
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MUC1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles. |
Disclaimer |
This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
MUC1 |
Accession # |
NP_001037855 |
Protein Gi # |
113206024 |
Ncbi Gene Id # |
4582 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
MUC1 |
Ncbi Official Full Name |
mucin 1, cell surface associated |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q7Z552 |
Background |
MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. |
1st Image Caption |
Antibody used in IHC on Human stomach at 1:500. |
2nd Image Caption |
Antibody used in IHC on Pig stomach at 1:500. |
3rd Image Caption |
Antibody used in WB on Human Jurkat 2.5 ug/ml. |
4th Image Caption |
Antibody used in IHC on Human Kidney at 4.0-8.0 ug/ml. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.