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AKR1C4 Antibody

AKR1C4 Antibody

ArtNr	PRS-22-933-50uL
Hersteller	ProSci
Menge	50 uL
Kategorie	Antibodies Western Blot Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AKR1C4, aldo-keto reductase family 1, member C4, HGNC:387, 3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581, 3-alpha hydroxysteroid dehydrogenase, type I, 3 alpha-hydroxysteroid dehydrogenase/dihydrodiol dehydrogenase 4, 3-alpha-hydroxysteroid dehydrogen
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Shipping	blue ice or RT
By Research Area	Cancer, Signal Transduction
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human AKR1C4 (NP_001809.3).
Applications	WB: 1:500 - 1:2000
Positive Control 1	A-549
Positive Control 2	SW620
Positive Control 3	Mouse liver
Positive Control 4	Mouse lung
Positive Control 5	Rat liver
Predicted Molecular Weight	Observed: 37kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	AKR1C4
Ncbi Gene Id #	1109
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	AKR1C4
Ncbi Official Full Name	aldo-keto reductase family 1, member C4
Ncbi Organism	Homo sapiens
Swissprot #	P17516
Background	This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
1st Image Caption	Western blot analysis of extracts of various cell lines, using AKR1C4 antibody (22-933) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 uL

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Lieferung vsl. bis 06.09.2024

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