ArtNr |
PRS-19-751-50uL |
Hersteller |
ProSci
|
Menge |
50 uL |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Liquid |
Applikationen |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
FBXL5, FBL4, FBL5, FLR1 |
Lieferbar |
|
Shipping |
blue ice or RT |
By Research Area |
Cell Cycle |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human FBXL5 (NP_036293.1). |
Applications |
WB: 1:500 - 1:1000
IHC: 1:50 - 1:100 |
Positive Control 1 |
293T |
Positive Control 2 |
Mouse eye |
Positive Control 3 |
Mouse brain |
Positive Control 4 |
Mouse lung |
Positive Control 5 |
Rat testis |
Positive Control 6 |
Rat lung |
Predicted Molecular Weight |
Observed: 79kDa |
Purification |
Affinity purification |
Clonality |
Polyclonal |
Isotype |
IgG |
Conjugate |
Unconjugated |
Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage Conditions |
Store at -20˚ C. Avoid freeze / thaw cycles. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
FBXL5 |
Ncbi Gene Id # |
26234 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
FBXL5 |
Ncbi Official Full Name |
F-box and leucine-rich repeat protein 5 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q9UKA1 |
Background |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus. |
1st Image Caption |
Western blot analysis of extracts of various cell lines, using FBXL5 antibody (19-751) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s. |
2nd Image Caption |
Immunohistochemistry of paraffin-embedded human stomach using FBXL5 antibody (19-751) at dilution of 1:100 (40x lens). |
3rd Image Caption |
Immunohistochemistry of paraffin-embedded human colon carcinoma using FBXL5 antibody (19-751) at dilution of 1:100 (40x lens). |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.