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PKP2 Antibody

PKP2 Antibody

ArtNr	PRS-19-705-50uL
Hersteller	ProSci
Menge	50 uL
Kategorie	Antibodies Western Blot Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	plakophilin-2, MGC177501, ARVD9, plakophilin 2, PKP2
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Shipping	blue ice or RT
By Research Area	Cell Cycle, Neuroscience, Signal Transduction
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 578-837 of human PKP2 (NP_001005242.2).
Applications	WB: 1:500 - 1:2000
Positive Control 1	Raji
Positive Control 2	Mouse kidney
Positive Control 3	Mouse liver
Positive Control 4	Rat kidney
Predicted Molecular Weight	Observed: 95-105kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	PKP2
Ncbi Gene Id #	5318
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	PKP2
Ncbi Official Full Name	plakophilin 2
Ncbi Organism	Homo sapiens
Swissprot #	Q99959
Background	This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.
1st Image Caption	Western blot analysis of extracts of various cell lines, using PKP2 antibody (19-705) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 uL

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Lieferung vsl. bis 06.09.2024

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