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ICAM3 Antibody

ICAM3 Antibody

ArtNr	PRS-19-214-50uL
Hersteller	ProSci
Menge	50 uL
Kategorie	Antibodies Western Blot Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Intercellular adhesion molecule 3, ICAM-3, CDw50, ICAM-R, CD50, ICAM3
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Shipping	blue ice or RT
By Research Area	Immunology, Neuroscience, Signal Transduction
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 270-490 of human ICAM3 (NP_002153.2).
Applications	WB: 1:1000 - 1:2000
Positive Control 1	LO2
Positive Control 2	A-549
Positive Control 3	SW480
Predicted Molecular Weight	Observed: 150kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	ICAM3
Ncbi Gene Id #	3385
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	ICAM3
Ncbi Official Full Name	intercellular adhesion molecule 3
Ncbi Organism	Homo sapiens
Swissprot #	P32942
Background	The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms.
1st Image Caption	Western blot analysis of extracts of various cell lines, using ICAM3 antibody (19-214) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 uL

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Lieferung vsl. bis 04.10.2024

Express-Lieferung: 9 Tage sparen

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