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CTSK Antibody

CTSK Antibody

ArtNr	PRS-18-119-50uL
Hersteller	ProSci
Menge	50 uL
Kategorie	Oncology Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot Primary Antibodies By Organ Testicular & Prostate Cancer
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IHC
Specific against	Mouse, Rat, Duck
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CTSK, cathepsin K, CTS02, CTSO, CTSO1, CTSO2, MGC23107, PKND, PYCD, cathepsin K (pycnodysostosis), cathepsin O1, cathepsin O2, cathepsin X
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Shipping	blue ice or RT
By Research Area	Cancer, Cell Cycle, Neuroscience, Signal Transduction
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 115-329 of human CTSK (NP_000387.1).
Applications	WB: 1:500 - 1:2000 IHC: 1:50 - 1:100
Positive Control 1	Mouse liver
Predicted Molecular Weight	Observed: 41kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	CTSK
Ncbi Gene Id #	1513
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	CTSK
Ncbi Official Full Name	cathepsin K
Ncbi Organism	Homo sapiens
Swissprot #	P43235
Background	The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.
1st Image Caption	Western blot analysis of extracts of mouse liver, using CTSK antibody (18-119) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
2nd Image Caption	Immunohistochemistry of paraffin-embedded mouse brain using CTSK antibody (18-119) at dilution of 1:100 (40x lens).
3rd Image Caption	Immunohistochemistry of paraffin-embedded rat brain using CTSK antibody (18-119) at dilution of 1:100 (40x lens).
4th Image Caption	Immunohistochemistry of paraffin-embedded mouse lung using CTSK antibody (18-119) at dilution of 1:100 (40x lens).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 uL

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Lieferung vsl. bis 06.09.2024

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