ArtNr |
PRS-16-716-50uL |
Hersteller |
ProSci
|
Menge |
50 uL |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Liquid |
Applikationen |
WB, IF, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
small leucine-rich protein 1B, proteoglycan core protein, dermatan sulphate proteoglycans II, decorin proteoglycan, bone proteoglycan II, SLRR1B, PGS2, PGII, PG40, DSPG2, CSCD, decorin, DCN |
Lieferbar |
|
Shipping |
blue ice or RT |
By Research Area |
Cell Cycle, Signal Transduction, Stem Cell |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 31-359 of human Decorin (NP_598010.1). |
Applications |
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200 |
Positive Control 1 |
Mouse heart |
Positive Control 2 |
Mouse liver |
Predicted Molecular Weight |
Observed: 49kDa |
Purification |
Affinity purification |
Clonality |
Polyclonal |
Isotype |
IgG |
Conjugate |
Unconjugated |
Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage Conditions |
Store at -20˚ C. Avoid freeze / thaw cycles. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
DCN |
Ncbi Gene Id # |
1634 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
DCN |
Ncbi Official Full Name |
decorin |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P07585 |
Background |
This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. |
1st Image Caption |
Western blot analysis of extracts of various cell lines, using Decorin antibody (16-716) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
2nd Image Caption |
Immunofluorescence analysis of MCF-7 cells using Decorin antibody (16-716). Blue: DAPI for nuclear staining. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.