Decorin Antibody

blue ice or RT

Recombinant fusion protein containing a sequence corresponding to amino acids 31-359 of human Decorin (NP_598010.1).

Mouse heart

Observed: 49kDa

Polyclonal

Unconjugated

Store at -20˚ C. Avoid freeze / thaw cycles.

None

1634

DCN

Homo sapiens

This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients.

Immunofluorescence analysis of MCF-7 cells using Decorin antibody (16-716). Blue: DAPI for nuclear staining.