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GGA2 Antibody

GGA2 Antibody

ArtNr	PRS-14-174-50uL
Hersteller	ProSci
Menge	50 uL
Kategorie	Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GGA2, KIAA1080, VEAR
Lieferbar
Shipping	blue ice or RT
By Research Area	Signal Transduction
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GGA2 (NP_055859.1).
Applications	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IF: 1:50 - 1:200
Positive Control 1	HepG2
Positive Control 2	Raji
Positive Control 3	MCF7
Positive Control 4	THP-1
Positive Control 5	22Rv1
Positive Control 6	Mouse brain
Predicted Molecular Weight	Observed: 72-80kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	GGA2
Ncbi Gene Id #	23062
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	GGA2
Ncbi Official Full Name	golgi-associated, gamma adaptin ear containing, ARF binding protein 2
Ncbi Organism	Homo sapiens
Swissprot #	Q9UJY4
Background	This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.
1st Image Caption	Western blot analysis of extracts of various cell lines, using GGA2 antibody (14-174) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.
2nd Image Caption	Immunohistochemistry of paraffin-embedded human kidney using GGA2 Antibody (14-174) at dilution of 1:200 (40x lens).
3rd Image Caption	Immunohistochemistry of paraffin-embedded human esophageal cancer using GGA2 Antibody (14-174) at dilution of 1:200 (40x lens).
4th Image Caption	Immunohistochemistry of paraffin-embedded human stomach using GGA2 Antibody (14-174) at dilution of 1:200 (40x lens).
5th Image Caption	Immunofluorescence analysis of MCF-7 cells using GGA2 antibody (14-174). Blue: DAPI for nuclear staining.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 uL

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Lieferung vsl. bis 06.09.2024

Express-Lieferung: 7 Tage sparen

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