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ENG Antibody

ENG Antibody

Hersteller	ProSci
Kategorie	Oncology Neuroscience Neuroinflammation Molecular Targets for Neuroscience Neural Development Antibodies By Cell Type Carcinoma Western Blot Primary Antibodies
Typ	Antibody Primary
Specific against	Human, Mouse, Rat
Format	Liquid
Applikationen	WB
Menge	100 uL
Host	Rabbit
ArtNr	PRS-13-161-100uL
eClass 6.1	32160702
eClass 9.0	32160702
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Alias	ENG, END, HHT1, ORW1
Shipping	blue ice or RT
By Research Area	Cancer, Immunology, Stem Cell
Immunogen	A synthetic peptide of human ENG
Applications	WB: 1:200 - 1:2000
Positive Control 1	LO2
Positive Control 2	HepG2
Positive Control 3	Mouse stomach
Positive Control 4	Mouse uterus
Positive Control 5	Mouse brain
Positive Control 6	Rat brain
Predicted Molecular Weight	Observed: 90kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, pH7.3.
Storage Conditions	Store at 4˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	ENG
Ncbi Gene Id #	2022
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	ENG
Ncbi Official Full Name	endoglin
Ncbi Organism	Homo sapiens
Swissprot #	P17813
Background	This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
1st Image Caption	Western blot analysis of extracts of various cell lines, using ENG antibody (13-161) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 uL

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