Vergleich

SARS-CoV-2 (COVID-19) Spike RBD Antibody

ArtNr PRS-9087-0.02mg
Hersteller ProSci
Menge 0.02 mg
Quantity options 0.02 mg 0.1 mg
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, IHC, ELISA
Specific against Virus
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
Citations Gorbalenya. bioRxiv: 2020.
Hui et al. Int J Infect Dis. 2020;91:264-266.
Belouzard et al. Viruses. 2012;4(6):1011-33.
Lee et al. J Virol. 2006;80(8):4079-87.
Wan et al. J Virol. 2020.
Wrapp et al. Science. 2020.
Heaton, et al. SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2. bioRxiv. 2020 Aug 14;2020.08.14.251207. doi: 10.1101/2020.08.14.251207.PMID: 32817937
NCBI S
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias SARS-CoV-2 (COVID-19) Spike RBD Antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),Surface Glycoprotein,Spike protein
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
SARS-CoV-2 (COVID-19) Spike RBD antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Manufacturer - Research Area
Infectious Disease, COVID-19
Background
Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019–20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection (3). The spike protein is the major target for neutralizing antibodies and vaccine development (4). The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19 (5). The recent study has shown that the SARS-CoV-2 spike protein binds ACE2 with higher affinity than SARS-CoV spike protein (6).
By Type
Infectious Disease, COVID-19
Badges
Trial Size, New, Most Images
Modifications
None
Protein Gi #
1791269090
Purification
SARS-CoV-2 (COVID-19) Spike RBD antibody is affinity chromatography purified via peptide column.
Isoforms
SARS-CoV-2 (COVID-19) Spike has one isoform (1273aa).
Concentration
1 mg/mL
Buffer
SARS-CoV-2 (COVID-19) Spike RBD antibody is supplied in PBS containing 0.02% sodium azide.
Application Note
WB: 2-5 μ g/mL; IF: 20 μ g/mL; IHC: 0.5 μ g/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry and Immunofluorescence in human samples. SARS-CoV-2 (COVID-19) Spike RBD Antibody can be used for the detection of SARS-CoV-2 (COVID-19) Spike protein in ELISA and WB. It will detect 4 ng of free peptide at 1 μ g/mL. All other applications and species not yet tested.
Homology
Predicted reactivity based on immunogen sequence: SARS-CoV Spike proteins: (63%)
Immunogen
Anti-SARS-CoV-2 (COVID-19) Spike RBD antibody (9087) was raised against a peptide corresponding to 19 amino acids near the carboxy terminus of SARS-CoV-2 (COVID-19) Spike glycoprotein RBD.

The immunogen is located within the last 50 amino acids of SARS-CoV-2 (COVID-19) Spike protein RBD.
Clonality
Polyclonal
NCBI Official Name
surface glycoprotein
NCBI Organism
Severe acute respiratory syndrome coronavirus 2
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.02 mg
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen