ArtNr |
ICH5002-1mg |
Hersteller |
IchorBio
|
Menge |
1mg |
Kategorie |
|
Typ |
Biosimilars |
Applikationen |
FA |
Specific against |
Human |
Host |
Humanized |
Isotype |
IgG4 |
Purity |
>95% by SDS-PAGE and HPLC |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Programmed cell death protein 1, Pdcd1, CD279 |
Lieferbar |
|
Specificity |
Detects human PD-1. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Toripalimab. |
Manufacturers Product Category |
Low endotoxin, biosimilar antibody |
Target Information |
PD-1 |
Isotype Information |
Human IgG4 |
Host Information |
Humanized |
Purification method |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Background |
Pembrolizumab biosimilar is a humanized monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2. It is an IgG4 kappa immunoglobulin with an approximate molecular weight of 149 kDa. |
Concentration |
1.0 - 5.0 mg/ml |
Formulation |
Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free. |
Endotoxin |
≤ 0.5 EU/mg as determined by the LAL method |
Storage |
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
Application Notes |
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients. |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.