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Ranibizumab Biosimilar - Research Grade Europäischer Partner

ArtNr ICH4031-50MG
Hersteller IchorBio
Menge 50 mg
Quantity options 10 mg 20 mg 2 mg 50 mg 5 mg
Kategorie
Typ Biosimilars
Specific against Human (Homo sapiens)
Isotype IgG1 Kappa
Purity >95% by SDS-PAGE and HPLC
Citations Gupta et al. Topical Delivery of Ranibizumab drops in Anti-aggregation diluent formula for retinal Delivery in Rabbits. ARVO Annual Meeting Abstract
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Vascular endothelial growth factor
Versandbedingung Gekühlt
Lieferbar
Specificity Detects human VEGF. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Ranibizumab. This product is for research use only.
Manufacturer - Type
Low endotoxin, biosimilar antibody
Manufacturer - Category
Low endotoxin, Biosimilar, recombinant antibody
Manufacturer - Isotype
Human IgG1 Kappa
Manufacturer - Targets
VEGF
Manufacturer - Host
Humanized
Shipping Temperature
Blue ice
Storage Conditions
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free.
Background
Ranibizumab is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment designed for intraocular use. Ranibizumab binds to and inhibits the biologic activity of human vascular endothelial growth factor A (VEGF-A). Ranibizumab, which lacks an Fc region, has a molecular weight of approximately 48 kilodaltons and is produced by CHO expression system.
Concentration
1.0 - 5.0 mg/ml
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity
Detects human VEGF. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Ranibizumab.
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Isotype Control
Bulk Human IgG1 Isotype Control (IB1) [ICH2254]
Buffer
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 mg
Lieferbar: In stock
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