ArtNr |
ICH4016-50MG |
Hersteller |
IchorBio
|
Menge |
50 mg |
Quantity options |
100 mg
10 mg
1 mg
20 mg
50 mg
5 mg
|
Kategorie |
|
Typ |
Biosimilars |
Specific against |
Human (Homo sapiens) |
Host |
Humanized |
Isotype |
IgG1 |
Purity |
>95% by SDS-PAGE and HPLC |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Proprotein convertase subtilisin/kexin type 9, <br />NARC-1, PC9 |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Specificity |
Detects human PCSK9. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Alirocumab. This product is for research use only. |
Manufacturer - Category |
Low endotoxin, Biosimilar, recombinant antibody |
Manufacturer - Isotype |
Human IgG1 |
Manufacturer - Targets |
PCSK9 |
Manufacturer - Host |
Humanized |
Shipping Temperature |
Blue ice |
Storage Conditions |
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
Formulation |
Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free. |
Background |
Alirocumab biosimilar is a human monoclonal antibody (IgG1 isotype) that targets proprotein convertase subtilisin kexin type 9 (PCSK9), is a PCSK9 inhibitor produced by recombinant DNA technology in Chinese Hamster Ovary cell suspension culture. Alirocumab biosimilar consists of two disulfide-linked human heavy chains, each covalently linked through a disulfide bond to a human kappa light chain. A single Nlinked glycosylation site is located in each heavy chain within the CH2 domain of the Fc constant region of the molecule. The variable domains of the heavy and light chains combine to form the PCSK9 binding site within the antibody. Alirocumab biosimilar has an approximate molecular weight of 146 kDa. |
Concentration |
1.0 - 5.0 mg/ml |
Endotoxin |
≤ 1.0 EU/mg as determined by the LAL method |
Manufacturer - Specificity |
Detects human PCSK9. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Alirocumab. |
Purification method |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
Isotype Control |
Bulk Human IgG1 Isotype Control (IB1) [ICH2254] |
Buffer |
ICH3001-100ml ICH3002-100ml ICH3003-100ml |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.