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Aflibercept Biosimilar - Research Grade Europäischer Partner

ArtNr ICH4015-1EA
Hersteller IchorBio
Menge 1 ea
Quantity options 1 ea 1 mg 20 mg 5 mg
Kategorie
Typ Biosimilars
Specific against Human (Homo sapiens)
Host Humanized
Isotype IgG1
Purity >95% by SDS-PAGE and HPLC
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Vascular endothelial growth factor
Versandbedingung Gekühlt
Lieferbar
Specificity Detects human VEGF. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Aflibercept. This product is for research use only.
Manufacturer - Category
Low endotoxin, Biosimilar, recombinant protein
Manufacturer - Isotype
Human IgG1
Manufacturer - Targets
VEGF
Manufacturer - Host
Humanized
Shipping Temperature
Blue ice
Storage Conditions
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free.
Background
Aflibercept biosimilar is a recombinant fusion protein consisting of portions of human VEGF receptors 1 and 2 extracellular domains fused to the Fc portion of human IgG1 formulated as an iso-osmotic solution for intravitreal administration. Aflibercept biosimilar is a dimeric glycoprotein with a protein molecular weight of 97 kilodaltons (kDa) and contains glycosylation, constituting an additional 15% of the total molecular mass, resulting in a total molecular weight of 115 kDa. Aflibercept biosimilar is produced in recombinant Chinese hamster ovary (CHO) cells.
Concentration
1.0 - 5.0 mg/ml
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity
Detects human VEGF. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Aflibercept.
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Isotype Control
Bulk Human IgG1 Isotype Control (IB1) [ICH2254]
Buffer
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 ea
Lieferbar: In stock
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