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Ado-Trastuzumab Emtansine Biosimilar - Research Grade

Ado-Trastuzumab Emtansine Biosimilar - Research Grade

ArtNr	ICH4014-1EA
Hersteller	IchorBio
Menge	1 ea
Quantity options	1 ea 20 mg 5 mg
Kategorie	Antibodies In Vivo Antibodies
Typ	Biosimilars
Specific against	Human (Homo sapiens)
Host	Humanized
Isotype	IgG1
Purity	>95% by SDS-PAGE and HPLC
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Receptor tyrosine-protein kinase erbB-2, MLN 19, HER2, HER2/neu
Versandbedingung	Gekühlt
Lieferbar
Specificity	Detects human HER2. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Ado-trastuzumab emtansine. This product is for research use only.
Manufacturer - Category	Low endotoxin, Biosimilar, ADC, recombinant antibody
Manufacturer - Isotype	Human IgG1
Manufacturer - Targets	HER2
Manufacturer - Host	Humanized
Shipping Temperature	Blue ice
Storage Conditions	Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation	Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free.
Background	Ado-trastuzumab emtansine is a HER2-targeted antibody-drug conjugate which contains the humanized anti-HER2 IgG1, trastuzumab, covalently linked to the microtubule inhibitory drug DM1 via the stable thioether linker MCC. Trastuzumab is produced by Chinese hamster ovary cells, and DM1-MCC are produced by chemical synthesis. Ado-trastuzumab emtansine contains an average of 3.5 DM1 molecules per antibody.
Concentration	1.0 - 5.0 mg/ml
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity	Detects human HER2. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Ado-trastuzumab emtansine.
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Isotype Control	Bulk Human IgG1 Isotype Control (IB1) [ICH2254]
Buffer	ICH3001-100ml ICH3002-100ml ICH3003-100ml

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Einfache Bestellung Periodische Bestellung

Menge: 1 ea

lieferbar

Lieferung vsl. bis 07.02.2025

Express-Lieferung: 18 Tage sparen

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