ArtNr |
ICH4007-20MG |
Hersteller |
IchorBio
|
Menge |
20 mg |
Quantity options |
100 mg
10 mg
1 mg
20 mg
50 mg
5 mg
|
Kategorie |
|
Typ |
Biosimilars |
Specific against |
Human (Homo sapiens) |
Host |
Humanized |
Isotype |
IgG1 |
Purity |
>95% by SDS-PAGE and HPLC |
Citations |
Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, ERBB, ERBB1, HER1 |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Specificity |
Detects human EGFR. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Matuzumab. This product is for research use only. |
Manufacturer - Category |
Low endotoxin, Biosimilar, recombinant antibody |
Manufacturer - Isotype |
Human IgG1 |
Manufacturer - Targets |
EGFR |
Manufacturer - Host |
Humanized |
Shipping Temperature |
Blue ice |
Storage Conditions |
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
Formulation |
Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free. |
Background |
Matuzumab biosimilar is a humanized IgG1 monoclonal antibody against human EGFR. As it only has approximately 10% murine origin it has limited immunogenicity, and being IgG1 it is capable of inducing antibody dependent cell cytotoxicity (ADCC).Matuzumab biosimilar is produced in mammalian (Chinese hamster ovary) cell culture. |
Concentration |
1.0 - 5.0 mg/ml |
Endotoxin |
≤ 1.0 EU/mg as determined by the LAL method |
Manufacturer - Specificity |
Detects human EGFR. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Matuzumab. |
Purification method |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
Isotype Control |
Bulk Human IgG1 Isotype Control (IB1) [ICH2254] |
Buffer |
ICH3001-100ml; ICH3002-100ml; ICH3003-100ml |