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Adalimumab Biosimilar - Research Grade Europäischer Partner

ArtNr ICH4001-5MG
Hersteller IchorBio
Menge 5mg
Kategorie
Typ Biosimilars
Specific against Human
Host Humanized
Isotype IgG1 Kappa
Purity >95% by SDS-PAGE and HPLC
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Cachectin, TNFa, Tumor necrosis factor ligand superfamily member 2, Tnfsf2
Lieferbar
Specificity Detects human TNF alpha. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Adalimumab. This product is for research use only.
Manufacturers Product Category
Low endotoxin, biosimilar antibody
Isotype Information
Human IgG1 Kappa
Host Information
Humanized
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution
Activated monocytes, neutrophils, macrophages, T cells, B cells, NK cells, LAK cells
Background
Adalimumab biosimilar is a recombinant human IgG1 monoclonal antibody specific for human tumor necrosis factor (TNF),was created using phage display technology resulting in an antibody with human derived heavy and light chain variable regions and human IgG1:k constant regions. Adalimumab biosimilar is produced by recombinant DNA technology in a mammalian cell (Chinese Hamster Ovary) expression system and is purified by a process that includes specific viral inactivation and removal steps. It consists of 1330 amino acids and has a molecular weight of approximately 148 kilodaltons.
Concentration
1.0 - 5.0 mg/ml
Formulation
Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free.
Endotoxin
≤ 0.5 EU/mg as determined by the LAL method
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 5mg
Lieferbar: In stock
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