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Adalimumab Biosimilar - Research Grade Europäischer Partner

ArtNr ICH4001-100mg
Hersteller IchorBio
Menge 100 mg
Quantity options 100 mg 10 mg 1 mg 20 mg 50 mg 5 mg
Kategorie
Typ Biosimilars
Specific against Human (Homo sapiens)
Host Humanized
Isotype IgG1 Kappa
Purity >95% by SDS-PAGE and HPLC
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Cachectin, TNFa, Tumor necrosis factor ligand superfamily member 2, Tnfsf2
Versandbedingung Gekühlt
Lieferbar
Specificity Detects human TNF alpha. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Adalimumab.
Manufacturer - Category
Low endotoxin, Biosimilar, recombinant antibody
Manufacturer - Isotype
Human IgG1 Kappa
Manufacturer - Targets
TNF alpha
Manufacturer - Host
Humanized
Shipping Temperature
Blue ice
Storage Conditions
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free.
Antigen Distribution
Activated monocytes, neutrophils, macrophages, T cells, B cells, NK cells, LAK cells
Background
Adalimumab biosimilar is a recombinant human IgG1 monoclonal antibody specific for human tumor necrosis factor (TNF),was created using phage display technology resulting in an antibody with human derived heavy and light chain variable regions and human IgG1:k constant regions. Adalimumab biosimilar is produced by recombinant DNA technology in a mammalian cell (Chinese Hamster Ovary) expression system and is purified by a process that includes specific viral inactivation and removal steps. It consists of 1330 amino acids and has a molecular weight of approximately 148 kilodaltons.
Concentration
1.0 - 5.0 mg/ml
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity
Detects human TNF alpha. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Adalimumab.
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Isotype Control
Bulk Human IgG1 Isotype Control (IB1) [ICH2254]
Buffer
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 mg
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 17.01.2025 

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