ArtNr |
ICH1183-5MG |
Hersteller |
IchorBio
|
Menge |
5 mg |
Quantity options |
100 mg
10 mg
1 mg
20 mg
25 mg
50 mg
5 mg
|
Kategorie |
|
Typ |
Antibody |
Applikationen |
FC, IF, IHC, Blocking, FA |
Clon |
10F.9G2 |
Specific against |
Mouse (Murine, Mus musculus) |
Host |
Mouse |
Isotype |
IgG1 |
Purity |
>95% by SDS-PAGE and HPLC |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Programmed cell death 1 ligand 1, Cd274, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1 |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Specificity |
Mouse anti-mouse PD-L1 antibody (10F.9G2) is a recombinant antibody where the original rat IgG2b backbone of 10F.9G2 has been changed to Mouse IgG1. This antibody recognizes an epitope on Mouse CD274 |
Manufacturer - Applications |
Flow Cytometry, Blocking, IHC (Frozen), Immunofluorescence, Functional Assays |
Manufacturer - Category |
Low Endotoxin, anti-mouse, recombinant antibody |
Manufacturer - Isotype |
Mouse IgG1 |
Manufacturer - Targets |
PD-L1 |
Shipping Temperature |
Blue ice |
Storage Conditions |
Mouse anti-mouse PD-L1 antibody (10F.9G2) is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -70oC. |
Aggregation |
Aggregation level ≤ 5% |
Formulation |
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
Antigen Distribution |
The CD274 antigien is present on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes |
Application Notes |
Each investigator should determine their own optimal working dilution for specific applications. |
Background |
CD274, also known as B7-H1 and PD-L1, is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. |
Concentration |
1.0 - 5.0 mg/ml |
Endotoxin |
≤ 1.0 EU/mg as determined by the LAL method |
Manufacturer - Specificity |
Mouse anti-mouse PD-L1 antibody (10F.9G2) is a recombinant antibody where the original rat IgG2b backbone of 10F.9G2 has been changed to Mouse IgG1. This antibody recognizes an epitope on Mouse CD274 |
Purification method |
This monoclonal antibody was purified using Protein A |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
Immunogen |
Unknown |
Isotype Control |
Mouse IgG1 Isotype Control for In Vivo - Low Endotoxin [HKSP] (ICH2247) |
Buffer |
ICH3001-100ml ICH3002-100ml ICH3003-100ml |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.