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Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody

Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody

ArtNr	ICH1182-50MG
Hersteller	IchorBio
Menge	50 mg
Quantity options	100 mg 10 mg 1 mg 20 mg 25 mg 50 mg 5 mg
Kategorie	Antibodies Primary Antibodies
Typ	Antibody
Applikationen	WB, FC, Blocking, FA
Clon	RMP1-14
Specific against	Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG2a
Purity	>95% by SDS-PAGE and HPLC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Programmed cell death protein 1, Pdcd1, CD279
Versandbedingung	Gekühlt
Lieferbar
Specificity	Mouse anti-PD-1 antibody (RMP1-14) is a recombinant antibody where the original Rat IgG2a backbone of clone RMP1-14 has been changed to Mouse IgG1. This antibody recognizes an epitope on Mouse PD-1
Manufacturer - Applications	Western Blot, Blocking, Flow Cytometry, Functional Assays
Manufacturer - Category	Low Endotoxin, anti-mouse, monoclonal antibody
Manufacturer - Isotype	Mouse IgG2a
Manufacturer - Targets	PD-1
Shipping Temperature	Blue ice
Storage Conditions	Mouse anti-mouse PD-1 antibody (RMP1-14) is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -70oC.
Aggregation	Aggregation level ≤ 5%
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution	Subset of double negative thymocytes, activated T and B cells
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Background	CD279, also known as programmed death-1 (PD-1) is a 50-55 kD immunoglobulin superfamily member. PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. This RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production.
Concentration	1.0 - 5.0 mg/ml
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity	Mouse anti-PD-1 antibody (RMP1-14) is a recombinant antibody where the original Rat IgG2a backbone of clone RMP1-14 has been changed to Mouse IgG1. This antibody recognizes an epitope on Mouse PD-1
Purification method	This monoclonal antibody was purified using Protein A
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen	Mouse PD-1 transfected BHK cells
Isotype Control	Mouse IgG1 Isotype Control for In Vivo - Low Endotoxin [HKSP] (ICH2247)
Buffer	ICH3001-100ml ICH3002-100ml ICH3003-100ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 mg

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Lieferung vsl. bis 07.02.2025

Express-Lieferung: 18 Tage sparen

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