ArtNr |
ICH1137-50MG |
Hersteller |
IchorBio
|
Menge |
50mg |
Kategorie |
|
Typ |
Antibody |
Applikationen |
WB, FC, IP, ELISA, Blocking |
Clon |
TR75-54.7 |
Specific against |
Mouse |
Host |
Hamster - Armenian |
Isotype |
IgG |
Purity |
>95% by SDS-PAGE and HPLC |
Citations |
Uncoupling immune trajectories of response and adverse events from anti-PD-1 immunotherapy in hepatocellular carcinoma |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Tnfrsf1b, Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, TNF-RII, TNFR-II, p75, p80 TNF-alpha receptor, CD120b, Tnfr-2 |
Lieferbar |
|
Specificity |
Anti-TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7) recognizes Mouse CD120 |
Manufacturers Product Category |
Low Endotoxin, anti-mouse |
Target Information |
TNFR2 |
Isotype Information |
Armenian Hamster IgG |
Purification method |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Background |
Tumor necrosis factor receptor II (TNF-RII) is present on most cell types and is considered to play a prominent role in stimulation by TNF-alpha. TNFRII proteins are expressed by hematopoietic cells including macrophages, neutrophils, lymphocytes, thymocytes and mast cells. It is expressed by a variety of other cell types including endothelial cells, cardiac myocytes and prostate cells |
Immunogen |
Purified Recombinant Mouse TNF R2 |
Concentration |
1.0 mg/ml |
Formulation |
0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
Endotoxin |
≤ 1.0 EU/mg as determined by the LAL method |
Aggregation |
Aggregation level ≤ 5% |
Storage |
anti-TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long-term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
Application Notes |
Blocking: Clone TR75-54.7 antibody has been reported to block ligand-induced receptor signaling. - Each investigator should determine their own optimal working dilution for specific applications. |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.