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Anti-Mouse TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7) Europäischer Partner

ArtNr ICH1137-100MG
Hersteller IchorBio
Menge 100mg
Kategorie
Typ Antibody
Applikationen WB, FC, IP, ELISA, Blocking
Clon TR75-54.7
Specific against Mouse
Host Hamster - Armenian
Isotype IgG
Purity >95% by SDS-PAGE and HPLC
Citations Uncoupling immune trajectories of response and adverse events from anti-PD-1 immunotherapy in hepatocellular carcinoma
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Tnfrsf1b, Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, TNF-RII, TNFR-II, p75, p80 TNF-alpha receptor, CD120b, Tnfr-2
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Specificity Anti-TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7) recognizes Mouse CD120
Manufacturers Product Category
Low Endotoxin, anti-mouse
Target Information
TNFR2
Isotype Information
Armenian Hamster IgG
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background
Tumor necrosis factor receptor II (TNF-RII) is present on most cell types and is considered to play a prominent role in stimulation by TNF-alpha. TNFRII proteins are expressed by hematopoietic cells including macrophages, neutrophils, lymphocytes, thymocytes and mast cells. It is expressed by a variety of other cell types including endothelial cells, cardiac myocytes and prostate cells
Immunogen
Purified Recombinant Mouse TNF R2
Concentration
1.0 mg/ml
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Aggregation
Aggregation level ≤ 5%
Storage
anti-TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long-term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Application Notes
Blocking: Clone TR75-54.7 antibody has been reported to block ligand-induced receptor signaling. - Each investigator should determine their own optimal working dilution for specific applications.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100mg
Lieferbar: In stock
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