ArtNr |
ICH1086-25MG |
Hersteller |
IchorBio
|
Menge |
25 mg |
Quantity options |
100 mg
1 mg
25 mg
50 mg
5 mg
|
Kategorie |
|
Typ |
Antibody |
Applikationen |
FC, IF, IHC, Blocking, FA |
Clon |
10F.9G2 |
Specific against |
Mouse (Murine, Mus musculus) |
Host |
Rat |
Isotype |
IgG2b Kappa |
Purity |
>95% by SDS-PAGE and HPLC |
Citations |
p16-dependent upregulation of PD-L1 impairs immunosurveillance of senescent cells Chen et al. NAT10/ac4C/FOXP1 Promotes Malignant Progression and Facilitates Immunosuppression by Reprogramming Glycolytic Metabolism in Cervical Cancer. Advanced Science Lin et al. Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice. Cell Reports |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Programmed cell death 1 ligand 1, Cd274, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1 |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Specificity |
Anti-PD-L1 In Vivo Antibody - Low Endotoxin (10F.9G2) recognizes an epitope on Mouse CD274 |
Manufacturer - Applications |
Flow Cytometry, Blocking, IHC (Frozen), Immunofluorescence, Functional Assays |
Manufacturer - Category |
Low Endotoxin, anti-mouse, monoclonal antibody |
Manufacturer - Isotype |
Rat IgG2b Kappa |
Manufacturer - Targets |
PD-L1 |
Shipping Temperature |
Blue ice |
Storage Conditions |
anti-PD-L1 In Vivo Antibody - Low Endotoxin (10F.9G2) is stable when stored at 2-8°C. Do not freeze. |
Aggregation |
Aggregation level ≤ 5% |
Formulation |
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
Antigen Distribution |
The CD274 antigien is present on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes |
Application Notes |
Each investigator should determine their own optimal working dilution for specific applications. |
Background |
CD274, also known as B7-H1 and PD-L1, is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. |
Concentration |
1.0 - 5.0 mg/ml |
Endotoxin |
<1.0 EU/mg as determined by the LAL method |
Manufacturer - Specificity |
Anti-PD-L1 In Vivo Antibody - Low Endotoxin (10F.9G2) recognizes an epitope on Mouse CD274 |
Purification method |
This monoclonal antibody was purified using Protein G |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
Immunogen |
Unknown |
Related Antibodies |
|
Isotype Control |
Rat IgG2b In Vivo Isotype Control - Low Endotoxin [1-2] (ICH2243) |
Buffer |
ICH3001-100ml ICH3002-100ml ICH3003-100ml |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.