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Anti-CTLA-4 (9H10) In Vivo Antibody - Ultra-Low Endotoxin Europäischer Partner

ArtNr ICH1084UL-50MG
Hersteller IchorBio
Menge 50 mg
Quantity options 100 mg 25 mg 50 mg 5 mg
Kategorie
Typ Antibody
Applikationen WB, FC, ELISA, Blocking
Clon 9H10
Specific against Mouse (Murine, Mus musculus)
Host Hamster - Syrian
Isotype IgG
Purity >98% by SDS-PAGE and HPLC
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Ctla4, Cytotoxic T-lymphocyte protein 4, CD152
Versandbedingung Gekühlt
Lieferbar
Specificity Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4
Manufacturer - Applications
Western Blot, Blocking, ELISA, Flow Cytometry
Manufacturer - Category
Ultra-Low Endotoxin, anti-mouse, monoclonal antibody
Manufacturer - Isotype
Syrian Hamster IgG
Manufacturer - Targets
CTLA-4
Shipping Temperature
Blue ice
Storage Conditions
anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Aggregation
Aggregation level ≤ 1%
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution
Activated T cells
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Background
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) also known as CD152, is a protein which is expressed on the surface of Helper T cells and plays an important regulatory role in the immune system. CTLA4 is a member of the immunoglobulin superfamily, expressed on the surface of Helper T cells. CTLA4 transmits an inhibitory signal to T cells. CTLA4 is potentially therapeutic in auto-immune diseases4, such as rheumatoid arthritis, HIV, autoimmune thyroid disease, multiple sclerosis and may also be useful during organ transplantation and cancer treatment. Clone 9H10 antibody has been shown to promote T cell co-stimulation by blocking CTLA4 binding, allowing for CD28 binding.
Concentration
1.0 - 5.0 mg/ml
Endotoxin
≤ 0.5 EU/mg as determined by the LAL method
Manufacturer - Specificity
Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4
Purification method
This monoclonal antibody was purified using Protein A
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen
Mouse CTLA-4-human IgG1 fusion protein
IMPACT Pathogen Test
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our hamster antibodies are tested for:
Mycoplasma spp
Mycoplasma pulmonis
Pneumonia virus of mice
Kilham's rat virus
Toolan's H1 virus
Hamster parvovirus
Lymphocytic choriomeningitis
Minute virus of mice
Theiler's murine encephalomyelitis virus
Sendai virus
Reovirus 3
Hantaan virus
Related Antibodies
Antibodies against the same target (Cat No.)
Buffer
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 mg
Lieferbar: In stock
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