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Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin Europäischer Partner

ArtNr ICH1069-25MG
Hersteller IchorBio
Menge 25 mg
Quantity options 100 mg 1 mg 25 mg 50 mg 5 mg
Kategorie
Typ Antibody
Applikationen WB, IP
Clon 55R-593
Specific against Mouse (Murine, Mus musculus)
Host Hamster - Armenian
Isotype IgG
Purity >95% by SDS-PAGE and HPLC
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Tumor necrosis factor receptor superfamily member 1A, Tnfrsf1a, TNF-R1, TNF-RI, p55, p60, CD120a
Versandbedingung Gekühlt
Lieferbar
Specificity Armenian Hamster anti-Mouse CD120A (Clone 55R-593) recognizes Mouse CD120A
Manufacturer - Applications
Immunoprecipitation, Western Blot
Manufacturer - Category
Low Endotoxin, anti-mouse, monoclonal antibody
Manufacturer - Isotype
Armenian Hamster IgG1
Manufacturer - Targets
TNF Receptor I
Shipping Temperature
Blue ice
Storage Conditions
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C.
Aggregation
Aggregation level ≤ 5%
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution
Variety of cell types at low levels
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Background
Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-A and TNF-B (also known as LT-A). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-ĸB induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.
Concentration
1.0 mg/ml
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity
Armenian Hamster anti-Mouse CD120A (Clone 55R-593) recognizes Mouse CD120A
Purification method
This monoclonal antibody was purified using Protein A
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen
E. coli-expressed extracellular domain of the mouse TNFRI protein
Antibodies against the same target (Cat No.)
Isotype Control
Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251)
Buffer
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 mg
Lieferbar: In stock
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