ArtNr |
ICH1046UL-100MG |
Hersteller |
IchorBio
|
Menge |
100mg |
Kategorie |
|
Typ |
Antibody |
Applikationen |
WB, FC, IP, IHC, ICC, FA |
Clon |
53-5.8 |
Specific against |
Mouse |
Host |
Rat |
Isotype |
IgG1 |
Purity |
>98% by SDS-PAGE and HPLC |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Cd8b, Lymphocyte antigen 3, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein Lyt-3, Cd8b1, Ly-3, Lyt-3, Lyt3 |
Lieferbar |
|
Specificity |
Anti-CD8 beta In Vivo Antibody - Ultra Low Endotoxin (53-5.8) recognizes an epitope on Mouse CD8b.2 |
Manufacturers Product Category |
Ultra-Low Endotoxin, anti-mouse |
Target Information |
CD8 beta |
Isotype Information |
Rat IgG1 |
Purification method |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Antigen Distribution |
The antibody 53-5.8 is specific for Ly-3.2 and has low reactivity with Ly-3.1 and is found on the majority of thymocytes, cytotoxic T cell subsets |
Background |
CD8b is the 32 kD β chain of CD8, also known as Lyt-3.2 or Ly-3.2. It is a member of the Ig superfamily expressed as a heterodimer with the CD8A chain on a subset of MHC class I-restricted T cells and most thymocytes. CD8 is a co-receptor for the TCR complex involved in T cell activation. |
Immunogen |
Mouse thymus or spleen |
Concentration |
1.0 - 5.0 mg/ml |
Formulation |
0.01 M phosphate buffered saline (PBS) pH 7.4 and does not contain BSA or sodium azide as a preservative. |
Endotoxin |
≤ 0.5 EU/mg as determined by the LAL method |
Aggregation |
Aggregation level ≤ 1% |
IMPACT Pathogen Test |
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our rat antibodies are tested for: - Mycoplasma spp - Mycoplasma pulmonis - Pneumonia virus of mice - Kilham's rat virus - Toolan's H1 virus - Rat parvovirus - Lymphocytic choriomeningitis virus - Rat cytomegalovirus - Sendai virus - Rat coronavirus - Sialodacryoadenitis virus - Rat minute virus - Seoul virus - Mouse adenovirus - Reovirus 3 - Rat theilovirus |
Storage |
anti-CD8 beta In Vivo Antibody - Ultra Low Endotoxin (53-5.8) is stable when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 80°C. Avoid Repeated Freeze Thaw Cycles. |
Application Notes |
Each investigator should determine their own optimal working dilution for specific applications. |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.