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Anti-CD3e (145-2C11) In Vivo Antibody - Low Endotoxin

Anti-CD3e (145-2C11) In Vivo Antibody - Low Endotoxin

ArtNr	ICH1041-25MG
Hersteller	IchorBio
Menge	25 mg
Quantity options	100 mg 1 mg 25 mg 50 mg 5 mg
Kategorie	Antibodies In Vivo Antibodies Blocking
Typ	Antibody
Applikationen	WB, FC, IP, IHC, Blocking, IV
Clon	145-2C11
Specific against	Mouse (Murine, Mus musculus)
Host	Hamster - Armenian
Isotype	IgG
Purity	>95% by SDS-PAGE and HPLC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	T3/Leu-4 epsilon chain, CD3 epsilon chain, CD3e
Versandbedingung	Gekühlt
Lieferbar
Specificity	Anti-CD3e In Vivo Antibody - Low Endotoxin (145-2C11) recognizes an epitope on Mouse CD3e
Manufacturer - Applications	IHC (Frozen), Flow Cytometry, Immunoprecipitation, Western Blot, In vivo Depletion, Blocking
Manufacturer - Category	Low Endotoxin, anti-mouse, monoclonal antibody
Manufacturer - Isotype	Armenian Hamster IgG
Manufacturer - Targets	CD3e
Shipping Temperature	Blue ice
Storage Conditions	anti-CD3e In Vivo Antibody - Low Endotoxin (145-2C11) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Aggregation	Aggregation level ≤ 5%
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution	The CD3 complex is present on thymocytes (differentiation dependent), mature T cells, NK-T cells of all mouse strains tested.
Application Notes	Blocking: The 145-2C11 antibody has been reported to block the binding of 17A2 antibody to CD3 epsilon-specific T cells Each investigator should determine their own optimal working dilution for specific applications.
Background	CD3e is a 20 kD transmembrane protein and is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
Concentration	1.0 mg/ml
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity	Anti-CD3e In Vivo Antibody - Low Endotoxin (145-2C11) recognizes an epitope on Mouse CD3e
Purification method	This monoclonal antibody was purified using Protein A
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen	H-2Kb-specific mouse cytotoxic T lymphocyte clone BM10-37
Related Antibodies	ICH1041UL-5MG
Antibodies against the same target (Cat No.)	ICH1040-1MG, ICH1040UL-5MG
Isotype Control	Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251)
Buffer	ICH3001-100ml ICH3002-100ml ICH3003-100ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 25 mg

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Lieferung vsl. bis 07.02.2025

Express-Lieferung: 18 Tage sparen

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