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Anti-Mouse CD3e In Vivo Antibody - Low Endotoxin (145-2C11)

Anti-Mouse CD3e In Vivo Antibody - Low Endotoxin (145-2C11)

ArtNr	ICH1041-100MG
Hersteller	IchorBio
Menge	100mg
Kategorie	Antibodies In Vivo Antibodies Blocking
Typ	Antibody
Applikationen	WB, FC, IP, IHC, Blocking, IV
Clon	145-2C11
Specific against	Mouse
Host	Hamster - Armenian
Isotype	IgG
Purity	>95% by SDS-PAGE and HPLC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	T3/Leu-4 epsilon chain, CD3 epsilon chain, CD3e
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Specificity	Anti-CD3e In Vivo Antibody - Low Endotoxin (145-2C11) recognizes an epitope on Mouse CD3e
Manufacturers Product Category	Low Endotoxin, anti-mouse
Isotype Information	Armenian Hamster IgG
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution	The CD3 complex is present on thymocytes (differentiation dependent), mature T cells, NK-T cells of all mouse strains tested.
Background	CD3e is a 20 kD transmembrane protein and is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
Immunogen	H-2Kb-specific mouse cytotoxic T lymphocyte clone BM10-37
Concentration	1.0 mg/ml
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Aggregation	Aggregation level ≤ 5%
Storage	anti-CD3e In Vivo Antibody - Low Endotoxin (145-2C11) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Application Notes	Blocking: The 145-2C11 antibody has been reported to block the binding of 17A2 antibody to CD3 epsilon-specific T cells - Each investigator should determine their own optimal working dilution for specific applications.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100mg

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Lieferung vsl. bis 20.12.2024

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