ArtNr |
ICH1037-100MG |
Hersteller |
IchorBio
|
Menge |
100 mg |
Quantity options |
100 mg
1 mg
25 mg
50 mg
5 mg
|
Kategorie |
|
Typ |
Antibody |
Applikationen |
WB, FC, IP, IHC, Blocking |
Clon |
16-10A1 |
Specific against |
Mouse (Murine, Mus musculus) |
Host |
Hamster - Armenian |
Isotype |
IgG |
Purity |
>95% by SDS-PAGE and HPLC |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Activation B7-1 antigen, B7 |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Specificity |
Anti-CD80 In Vivo Antibody - Low Endotoxin (16-10A1) recognizes an epitope on Mouse CD80 |
Manufacturer - Applications |
Immunoprecipitation, Western Blot, Blocking, Flow Cytometry, IHC (Frozen) |
Manufacturer - Category |
Low Endotoxin, anti-mouse, monoclonal antibody |
Manufacturer - Isotype |
Armenian Hamster IgG |
Manufacturer - Targets |
CD80 |
Shipping Temperature |
Blue ice |
Storage Conditions |
anti-CD80 In Vivo Antibody - Low Endotoxin (16-10A1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
Aggregation |
Aggregation level ≤ 5% |
Formulation |
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
Antigen Distribution |
Mouse CD80 is expressed on Activated B-Cells, Activated T-Cells, macrophages, and dendritic cells. |
Application Notes |
Each investigator should determine their own optimal working dilution for specific applications. |
Background |
CD80 (B7-1) is a type I integral membrane protein related very closely to CD86 (B7-2). A main function of CD80 is the costimulation of T-cells through ligation of CD28 and CD152 (CTLA-4). T-cells activate with binding of CD28 to CD80 and binding of CD80 to CTLA-4 results in inhibition of T-cells. The clone 16-10A1 has the ability to block the costimulatory activity of CD80 while exhibiting no effect on the activity of CD86. |
Concentration |
1.0 mg/ml |
Endotoxin |
≤ 1.0 EU/mg as determined by the LAL method |
Manufacturer - Specificity |
Anti-CD80 In Vivo Antibody - Low Endotoxin (16-10A1) recognizes an epitope on Mouse CD80 |
Purification method |
This monoclonal antibody was purified using Protein A |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
Immunogen |
Purified Recombinant Mouse CD80 (>98%) |
Related Antibodies |
|
Isotype Control |
Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251) |
Buffer |
ICH3001-100ml ICH3002-100ml ICH3003-100ml |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.