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Bulk anti-Human HLA-DR antibody (L243)

Bulk anti-Human HLA-DR antibody (L243)

ArtNr	ICH1026-50MG
Hersteller	IchorBio
Menge	50mg
Kategorie	Oncology Antibodies In Vivo Antibodies By Cell Type Carcinoma Western Blot Blocking
Typ	Antibody
Applikationen	WB, FC, IP, IHC, Blocking
Clon	L243
Specific against	Human
Host	Mouse
Isotype	IgG2a
Purity	>95% by SDS-PAGE and HPLC
Citations	WNT4 promotes macrophage polarization via granulosa cell M-CSF and reduces granulosa cell apoptosis in endometriosis
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Major Histocompatibility Class II, MHC class II, HLA-DR Monomorphic
Lieferbar
Specificity	Anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) recognizes/reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross-react with HLA-DP and HLA-DQ
Manufacturers Product Category	Low Endotoxin, anti-human
Target Information	HLA-DR
Isotype Information	Mouse IgG2a
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution	The HLA-DR antigen is present on B-lymphocytes, activated T-lymphocytes and activated natural killer (NK) lymphocytes. This antigen is also expressed on monocytes, macrophages, human progenitor cells and B-cell lymphomas.
Background	HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD (heavy) chain & a 27 kD (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, and dendritic cells. HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Clone L243 binds a conformational epitope on HLA-DRalpha which depends on the correct folding of the Aβ heterodimer.
Immunogen	Unknown
Concentration	1.0 mg/ml
Formulation	No carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4.
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Aggregation	Aggregation level ≤ 5%
Storage	anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) is stable for at least four (4) weeks when stored at 2-8°C. For long-term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50mg

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Lieferung vsl. bis 20.12.2024

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