ArtNr |
ICH1026-25MG |
Hersteller |
IchorBio
|
Menge |
25 mg |
Quantity options |
100 mg
1 mg
25 mg
50 mg
5 mg
|
Kategorie |
|
Typ |
Antibody |
Applikationen |
WB, FC, IP, IHC, Blocking |
Clon |
L243 |
Specific against |
Human (Homo sapiens) |
Host |
Mouse |
Isotype |
IgG2a |
Purity |
>95% by SDS-PAGE and HPLC |
Citations |
WNT4 promotes macrophage polarization via granulosa cell M-CSF and reduces granulosa cell apoptosis in endometriosis |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Major Histocompatibility Class II, MHC class II, HLA-DR Monomorphic |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Specificity |
Anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) recognizes/reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross-react with HLA-DP and HLA-DQ |
Manufacturer - Applications |
Western Blot, Blocking, Flow Cytometry, Immunoprecipitation, CyTOF, IHC (Frozen) |
Manufacturer - Category |
Low Endotoxin, anti-human, monoclonal antibody |
Manufacturer - Isotype |
Mouse IgG2a |
Manufacturer - Targets |
HLA-DR |
Shipping Temperature |
Blue ice |
Storage Conditions |
anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) is stable for at least four (4) weeks when stored at 2-8°C. For long-term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
Aggregation |
Aggregation level ≤ 5% |
Formulation |
No carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4. |
Antigen Distribution |
The HLA-DR antigen is present on B-lymphocytes, activated T-lymphocytes and activated natural killer (NK) lymphocytes. This antigen is also expressed on monocytes, macrophages, human progenitor cells and B-cell lymphomas. |
Application Notes |
Each investigator should determine their own optimal working dilution for specific applications. |
Background |
HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD (heavy) chain & a 27 kD (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, and dendritic cells. HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Clone L243 binds a conformational epitope on HLA-DRalpha which depends on the correct folding of the Aβ heterodimer. |
Concentration |
1.0 mg/ml |
Endotoxin |
≤ 1.0 EU/mg as determined by the LAL method |
Manufacturer - Specificity |
Anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) recognizes/reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross-react with HLA-DP and HLA-DQ |
Purification method |
This monoclonal antibody was purified using Protein A |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
Immunogen |
Unknown |
Isotype Control |
Mouse IgG2a In Vivo Isotype Control - Low Endotoxin [C1.18.4] (ICH2245) |
Buffer |
ICH3001-100ml ICH3002-100ml ICH3003-100ml |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.