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Anti-Human HLA-DR In Vivo Antibody - Low Endotoxin (L243) Europäischer Partner

ArtNr ICH1026-1MG
Hersteller IchorBio
Menge 1mg
Kategorie
Typ Antibody
Applikationen WB, Blocking
Clon L243
Specific against Human
Host Mouse
Isotype IgG2a
Purity >95% by SDS-PAGE and HPLC
ECLASS 5.1 32160702
ECLASS 6.1 32160702
ECLASS 8.0 32160702
ECLASS 9.0 32160702
ECLASS 10.0.1 32160702
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias in vivo
Lieferbar
Specificity Anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) recognizes/reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross-react with HLA-DP and HLA-DQ
Aggregation
Aggregation level <= 5%
Antigen Distribution
The HLA-DR antigen is present on B-lymphocytes, activated T-lymphocytes and activated natural killer (NK) lymphocytes. This antigen is also expressed on monocytes, macrophages, human progenitor cells and B-cell lymphomas.
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Background
HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD (heavy) chain & a 27 kD (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, and dendritic cells. HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Clone L243 binds a conformational epitope on HLA-DRalpha which depends on the correct folding of the Abeta heterodimer.
Concentration
1.0 mg/ml
Endotoxin
<= 1.0 EU/mg as determined by the LAL method
Formulation
No carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4.
Immunogen
Unknown
Product Type
Low Endotoxin, anti-human
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Storage
anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) is stable for at least four (4) weeks when stored at 2-8C. For long-term storage, aliquot in working volumes without diluting and store at - 20C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1mg
Lieferbar: In stock
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