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Bulk Anti-Human CD16 (3G8) Antibody Europäischer Partner

ArtNr ICH1010-50MG
Hersteller IchorBio
Menge 50 mg
Quantity options 100 mg 1 mg 25 mg 50 mg 5 mg
Kategorie
Typ Antibody
Applikationen FC, IP, IHC, Blocking
Clon 3G8
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Purity >95% by SDS-PAGE and HPLC
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias FCGR3A, Fc-gamma RIII, FcRIII
Versandbedingung Gekühlt
Lieferbar
Specificity Anti-CD16 In Vivo Antibody - Low Endotoxin (3G8) recognizes an epitope on Human CD16
Manufacturer - Applications
IHC (Frozen), Flow Cytometry, Immunoprecipitation, Blocking, CyTOF
Manufacturer - Category
Low Endotoxin, anti-human, monoclonal antibody
Manufacturer - Isotype
Mouse IgG1 Kappa
Manufacturer - Targets
CD16
Shipping Temperature
Blue ice
Storage Conditions
anti-CD16 In Vivo Antibody - Low Endotoxin (3G8) is stable when stored at 2-8°C.
Aggregation
Aggregation level ≤ 5%
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, without BSA or sodium azide added.
Antigen Distribution
CD16 is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans.
Application Notes
Flow Cytometry: For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume.
Blocking: Clone 3G8 antibody blocks neutrophil phagocytosis and stimulates NK cell proliferation.
Each investigator should determine their own optimal working dilution for specific applications.
Background
CD16 is known as low affinity IgG receptor III (Fc gamma RIII) and is expressed as two distinct forms (CD16a and CD16b). CD16a (Fc gamma RIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. CD16b (Fc gamma RIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils.
Concentration
≥ 2.0 mg/ml
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity
Anti-CD16 In Vivo Antibody - Low Endotoxin (3G8) recognizes an epitope on Human CD16
Purification method
This monoclonal antibody was purified using Protein A
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen
Human PMN cells
Antibodies against the same target (Cat No.)
Isotype Control
Mouse IgG1 Isotype Control for In Vivo - Low Endotoxin [HKSP] (ICH2247)
Buffer
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 mg
Lieferbar: In stock
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