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NKX2-1 Antibody

NKX2-1 Antibody

ArtNr	CSB-RA181189A0HU-100ul
Hersteller	Cusabio
Menge	100ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling Antibodies By Cell Type Hematology Leukemia Lymphoma Flow Cytometry Immunohistochemistry Western Blot ELISA Primary Antibodies By Organ Lung Cancer Bladder Cancer Thyroid Cancer
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, FC, IHC, ELISA
Clon	6C11
Specific against	Human
Host	Rabbit
Isotype	IgG
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Homeobox protein Nkx-2.1 (Homeobox protein NK-2 homolog A) (Thyroid nuclear factor 1) (Thyroid transcription factor 1) (TTF-1) (Thyroid-specific enhancer-binding protein) (T/EBP), NKX2-1, NKX2A TITF1 TTF1, Homeobox protein Nkx-2.1 (Homeobox protein NK-2 homolog A) (Thyroid nuclear factor 1) (Thyroid transcription factor 1) (TTF-1) (Thyroid-specific enhancer-binding protein) (T/EBP), NKX2-1, NKX2A TITF1 TTF1
Similar products	NKX2-1, Homeobox protein Nkx-2.1 (Homeobox protein NK-2 homolog A) (Thyroid nuclear factor 1) (Thyroid transcription factor 1) (TTF-1) (Thyroid-specific enhancer-binding protein) (T/EBP), NKX2A TITF1 TTF1
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UniProt ID	P43699
Immunogen	A synthesized peptide derived from human TTF1
Tested Applications	ELISA, WB, IHC, FC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, FC:1:20-1:200
Background	Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity).
Conjugate	Non-conjugated
Buffer	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage	Upon receipt, store at -20CC or -80CC. Avoid repeated freeze.
Purification Method	Affinity-chromatography
Modified	Epigenetics and Nuclear Signaling

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Menge: 100ul

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Lieferung vsl. bis 30.08.2024

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