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UPF2 Antibody

ArtNr CSB-PA867186DSR2HU-50ul
Hersteller Cusabio
Menge 50ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen IHC, ELISA
Specific against Human
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias DKFZp434D222 antibody; hUpf2 antibody; KIAA1408 antibody; MGC138834 antibody; MGC138835 antibody; Nonsense mRNA reducing factor 2 antibody; Regulator of nonsense transcripts 2 antibody; RENT2 antibody; RENT2_HUMAN antibody; Smg 3 antibody; Smg 3 homolog nonsense mediated mRNA decay factor antibody; Up-frameshift suppressor 2 homolog antibody; UPF2 antibody; UPF2 regulator of nonsense transcripts homolog antibody; UROC1 antibody; Urocanate hydratase antibody; Yeast Upf2p homolog antibody, Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2), UPF2, KIAA1408 RENT2
Similar products UPF2, Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2), KIAA1408 RENT2
Lieferbar
Immunogen Species
Human
UniprotID
Q9HAU5
Immunogen
Recombinant Human Regulator of nonsense transcripts 2 protein (1153-1272AA)
Applications info
ELISA, IHC, Recommended dilution: IHC:1:20-1:200
Dilution ratio 1
ELISA:1:2000-1:10000
Dilution ratio 2
IHC:1:20-1:200
Background
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA.
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage
Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method
Antigen Affinity Purified
General Research Areas
Epigenetics and Nuclear Signaling
Initial Research Areas
Epigenetics and Nuclear Signaling

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50ul
Lieferbar: In stock
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