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MACROD1 Antibody, HRP conjugated

MACROD1 Antibody, HRP conjugated

ArtNr	CSB-PA860244LB01HU-50ug
Hersteller	Cusabio
Menge	50ug
Quantity options	100ug 50ug
Kategorie	Antibodies ELISA Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG
Konjugat/Tag	HRP
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MACROD1 antibody; LRP16 antibody; ADP-ribose glycohydrolase MACROD1 antibody; MACRO domain-containing protein 1 antibody; O-acetyl-ADP-ribose deacetylase MACROD1 antibody; EC 3.1.1.106 antibody; Protein LRP16 antibody; [Protein ADP-ribosylaspartate] hydrolase MACROD1 antibody; EC 3.2.2.- antibody; [Protein ADP-ribosylglutamate] hydrolase MACROD1 antibody; EC 3.2.2.- antibody, O-acetyl-ADP-ribose deacetylase MACROD1 (EC 3.2.2.-) (EC 3.5.1.-) (MACRO domain-containing protein 1) (Protein LRP16) ([Protein ADP-ribosylglutamate] hydrolase), MACROD1, LRP16
Similar products	MACROD1, O-acetyl-ADP-ribose deacetylase MACROD1 (EC 3.2.2.-) (EC 3.5.1.-) (MACRO domain-containing protein 1) (Protein LRP16) ([Protein ADP-ribosylglutamate] hydrolase), LRP16
Lieferbar
Immunogen Species	Human
UniprotID	Q9BQ69
Immunogen	Recombinant Human O-acetyl-ADP-ribose deacetylase MACROD1 protein (83-325AA)
Applications info	ELISA
Background	Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen. May play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. Could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction. Could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. Enhances ESR1-mediated transcription activity.
Conjugate	HRP
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling, Cancer, Signal transduction
Initial Research Areas	Signal Transduction

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50ug

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Lieferung vsl. bis 01.11.2024

Express-Lieferung: 2 Tage sparen

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