ArtNr |
CSB-PA741122LA01HU-50ug |
Hersteller |
Cusabio
|
Menge |
50ug |
Quantity options |
100ug
20ug
50ug
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
WB, IF, IHC, ELISA |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
4 antibody; 5)-dependent Rac exchanger 2 antibody; 5-trisphosphate-dependent Rac exchanger 2 protein antibody; 6230420N16Rik antibody; DEP domain-containing protein 2 antibody; DEP.2 antibody; DEPDC2 antibody; FLJ12987 antibody; P-Rex2 antibody; Phosphatidylinositol 3 antibody; phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 antibody; phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein antibody; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 antibody; PREX2 antibody; PREX2_HUMAN antibody; PtdIns(3 antibody; PtdIns(3,4,5)-dependent Rac exchanger 2 antibody, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (P-Rex2) (PtdIns(3,4,5)-dependent Rac exchanger 2) (DEP domain-containing protein 2), PREX2, DEPDC2 |
Similar products |
Phosphatidylinositol 3, 4, PREX2, DEPDC2, 5-trisphosphate-dependent Rac exchanger 2 protein (P-Rex2) (PtdIns(3, 5)-dependent Rac exchanger 2) (DEP domain-containing protein 2) |
Lieferbar |
|
Immunogen Species |
Human |
UniprotID |
Q70Z35 |
Immunogen |
Recombinant Human Phosphatidylinositol 3, 4, 5-trisphosphate-dependent Rac exchanger 2 protein (1417-1592AA) |
Applications info |
ELISA, WB, IHC, IF, Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Dilution ratio 1 |
ELISA:1:2000-1:10000 |
Dilution ratio 2 |
WB:1:2000-1:5000 |
Dilution ratio 3 |
IHC:1:20-1:200 |
Dilution ratio 4 |
IF:1:50-1:200 |
Background |
Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3, 4, 5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase. |
Conjugate |
Non-conjugated |
Buffer |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
>95%, Protein G purified |
General Research Areas |
Signal transduction |
Initial Research Areas |
Signal Transduction |
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