ArtNr |
CSB-PA621883LC01HU-50ug |
Hersteller |
Cusabio
|
Menge |
50ug |
Quantity options |
100ug
50ug
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
Konjugat/Tag |
FITC |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
KISS 1 antibody; KiSS 1 metastasis suppressor antibody; Kiss1 antibody; KISS1_HUMAN antibody; Kisspeptin 1 antibody; Kisspeptin 10 antibody; Kisspeptin 13 antibody; Kisspeptin 14 antibody; Kisspeptin antibody; Kisspeptin-1 antibody; Kisspeptin-10 antibody; Kisspeptin-54 antibody; Kisspeptin1 antibody; Malignant melanoma metastasis suppressor antibody; Metastasis suppressor KiSS 1 antibody; Metastasis suppressor KiSS1 antibody; Metastin antibody; MGC39258 antibody, Metastasis-suppressor KiSS-1 (Kisspeptin-1) [Cleaved into: Metastin (Kisspeptin-54), Kisspeptin-14, Kisspeptin-13, Kisspeptin-10], KISS1 |
Similar products |
KISS1, Metastasis-suppressor KiSS-1 (Kisspeptin-1) [Cleaved into: Metastin (Kisspeptin-54), Kisspeptin-14, Kisspeptin-13, Kisspeptin-10] |
Lieferbar |
|
Immunogen Species |
Human |
UniprotID |
Q15726 |
Immunogen |
Recombinant Human Metastasis-suppressor KiSS-1 protein (20-138AA) |
Applications info |
ELISA |
Background |
Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-10, but not other kisspeptins, increased intracellular Ca(2+) levels in isolated first trimester trophoblasts. Kp-10 is a paracrine/endocrine regulator in fine-tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. |
Conjugate |
FITC |
Buffer |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
>95%, Protein G purified |
General Research Areas |
Epigenetics and Nuclear Signaling, Neuroscience, Cancer, Cell biology |
Initial Research Areas |
Cell Biology |
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