ArtNr |
CSB-PA619753LD01HU-50ug |
Hersteller |
Cusabio
|
Menge |
50ug |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
Konjugat/Tag |
Biotin |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Liver X receptor alpha antibody; LXR a antibody; LXRA antibody; NR1H3 antibody; NR1H3_HUMAN antibody; Nuclear receptor subfamily 1 group H member 3 antibody; Oxysterols receptor LXR alpha antibody; Oxysterols receptor LXR-alpha antibody; RLD 1 antibody; RLD1 antibody, Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear receptor subfamily 1 group H member 3), NR1H3, LXRA |
Similar products |
NR1H3, LXRA, Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear receptor subfamily 1 group H member 3) |
Lieferbar |
|
Immunogen Species |
Human |
UniprotID |
Q13133 |
Immunogen |
Recombinant Human Oxysterols receptor LXR-alpha protein (1-402AA) |
Applications info |
ELISA |
Background |
Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:19481530, PubMed:25661920). Interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES (By similarity). LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides (By similarity). Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8 (PubMed:19481530). Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). |
Conjugate |
Biotin |
Buffer |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
>95%, Protein G purified |
General Research Areas |
Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Metabolism, Signal transduction |
Initial Research Areas |
Cardiovascular |
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