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DNAJC3 Antibody, Biotin conjugated

DNAJC3 Antibody, Biotin conjugated

ArtNr	CSB-PA615670LD01HU-50ug
Hersteller	Cusabio
Menge	50ug
Quantity options	100ug 50ug
Kategorie	Antibodies ELISA Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Biotin
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DnaJ (Hsp40) homolog subfamily C member 3 antibody; DnaJ homolog subfamily C member 3 antibody; DNAJC3 antibody; DNJC3_HUMAN antibody; double-stranded RNA-activated protein kinase inhibitor antibody; Endoplasmic reticulum DnaJ protein 6 antibody; ERdj6 antibody; HP58 antibody; Interferon induced; double stranded RNA activated protein kinase inhibitor antibody; Interferon-induced antibody; P58 antibody; p58 ipk antibody; P58IPK antibody; PRKRI antibody; Protein kinase inhibitor of 58 kDa antibody; Protein kinase inhibitor p58 antibody; Protein kinase interferon inducible double stranded RNA dependent inhibitor antibody, DnaJ homolog subfamily C member 3 (Endoplasmic reticulum DNA J domain-containing protein 6) (ER-resident protein ERdj6) (ERdj6) (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58), DNAJC3, P58IPK PRKRI
Similar products	DNAJC3, DnaJ homolog subfamily C member 3 (Endoplasmic reticulum DNA J domain-containing protein 6) (ER-resident protein ERdj6) (ERdj6) (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58), P58IPK PRKRI
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Immunogen Species	Human
UniprotID	Q13217
Immunogen	Recombinant Human DnaJ homolog subfamily C member 3 protein (277-496AA)
Applications info	ELISA
Background	Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions (By similarity). Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
Conjugate	Biotin
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling, Microbiology, Signal transduction
Initial Research Areas	Microbiology

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50ug

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Lieferung vsl. bis 27.09.2024

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