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U2AF2 Antibody, FITC conjugated

ArtNr CSB-PA025408LC01HU-50ug
Hersteller Cusabio
Menge 50ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen ELISA
Specific against Human
Host Rabbit
Isotype IgG
Konjugat/Tag FITC
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias hU2AF(65) antibody; hU2AF65 antibody; Splicing factor U2AF 65 kDa subunit antibody; U2 (RNU2) small nuclear RNA auxiliary factor 2 antibody; U2 auxiliary factor 65 kDa subunit antibody; U2 small nuclear ribonucleoprotein auxiliary factor (65kD) antibody; U2 small nuclear RNA auxiliary factor 2 antibody; U2 snRNP auxiliary factor large subunit antibody; U2af2 antibody; U2AF2_HUMAN antibody; U2AF65 antibody, Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit), U2AF2, U2AF65
Similar products U2AF2, U2AF65, Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Lieferbar
Immunogen Species
Human
UniprotID
P26368
Immunogen
Recombinant Human Splicing factor U2AF 65 kDa subunit protein (124-246AA)
Applications info
ELISA
Background
Necessary for the splicing of pre-mRNA. By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-terminal domain (CTD), and thereby pre-mRNA, may couple transcription to splicing (PubMed:21536736). Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Represses the splicing of MAPT/Tau exon 10.
Conjugate
FITC
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage
Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method
>95%, Protein G purified
General Research Areas
Epigenetics and Nuclear Signaling
Initial Research Areas
Epigenetics and Nuclear Signaling

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50ug
Lieferbar: In stock
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Lieferung vsl. bis 30.08.2024 

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