ArtNr |
CSB-PA019213EC01HU-50ug |
Hersteller |
Cusabio
|
Menge |
50ug |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
Konjugat/Tag |
FITC |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
RAB 5 antibody; RAB 5A antibody; RAB5A antibody; RAB5A member RAS oncogene family antibody; RAB5A_HUMAN antibody; RAS associated protein RAB5A antibody; Ras related protein Rab 5A antibody; Ras-related protein Rab-5A antibody, Ras-related protein Rab-5A, RAB5A, RAB5 |
Similar products |
RAB5A, RAB5, Ras-related protein Rab-5A |
Lieferbar |
|
Immunogen Species |
Human |
UniprotID |
P20339 |
Immunogen |
Recombinant Human Ras-related protein Rab-5A protein (1-215AA) |
Applications info |
ELISA |
Background |
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes (PubMed:10818110, PubMed:14617813, PubMed:16410077, PubMed:15378032). Contributes to the regulation of filopodia extension (PubMed:14978216). Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan (PubMed:22660413). Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3 (By similarity). |
Conjugate |
FITC |
Buffer |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
>95%, Protein G purified |
General Research Areas |
Neuroscience, Tags & Cell Markers, Signal transduction |
Initial Research Areas |
Neuroscience |
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