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PQBP1 Antibody, Biotin conjugated

PQBP1 Antibody, Biotin conjugated

ArtNr	CSB-PA018594LD01HU-50ug
Hersteller	Cusabio
Menge	50ug
Quantity options	100ug 50ug
Kategorie	Antibodies ELISA Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Biotin
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	38 kDa nuclear protein containing a WW domain antibody; Mental retardation; X linked 55 antibody; MRX55 antibody; MRXS3 antibody; MRXS8 antibody; Npw38 antibody; Nuclear protein containing WW domain 38 kD antibody; OTTHUMP00000025808 antibody; Polyglutamine binding protein 1 antibody; Polyglutamine tract binding protein 1 antibody; Polyglutamine tract-binding protein 1 antibody; Polyglutamine-binding protein 1 antibody; PQBP 1 antibody; PQBP-1 antibody; PQBP1 antibody; PQBP1_HUMAN antibody; RENS1 antibody; SHS antibody; Sutherland Haan X linked mental retardation syndrome antibody, Polyglutamine-binding protein 1 (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38) (Polyglutamine tract-binding protein 1), PQBP1, NPW38
Similar products	PQBP1, NPW38, Polyglutamine-binding protein 1 (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38) (Polyglutamine tract-binding protein 1)
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Immunogen Species	Human
UniprotID	O60828
Immunogen	Recombinant Human Polyglutamine-binding protein 1 protein (2-265AA)
Applications info	ELISA
Background	Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species (PubMed:23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.
Conjugate	Biotin
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling, Neuroscience, Cancer, Metabolism, Signal transduction
Initial Research Areas	Neuroscience

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Lieferung vsl. bis 27.09.2024

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