Acetyl-H2AFZ (K4) Antibody

P0C0S5

ELISA, WB, ICC, IF, IP, ChIP, Recommended dilution: WB:1:200-1:2000, ICC:1:10-1:100, IF:1:10-1:100, IP:1:200-1:2000

WB:1:200-1:2000

IF:1:10-1:100

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Antigen Affinity Purified

Epigenetics and Nuclear Signaling