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USP9x polyclonal antibody

ArtNr BS91419-100
Hersteller Bioworld Technology, Inc
Menge 100 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Primary
Applikationen WB, FC, IF, IHC, ICC
Specific against Human, Mouse, Rat
Host Rabbit
Konjugat/Tag Unconjugated
Purity ProA affinity purified
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias hFAM, USP9X, DFFRX, FAM, USP9, Deubiquitinating enzyme FAF X, Deubiquitinating enzyme FAF-X, DFFRX, Drosophila fat facets related X linked, FAF, Fafl, Fam, Fat facets homolog, Fat facets in mammals, Fat facets protein related X linked, Fat facets protein related, X-linked, Fat facets protein-related, hFAM, MRX99, Probable ubiquitin carboxyl terminal hydrolase FAF X, Probable ubiquitin carboxyl-terminal hydrolase FAF-X, Ubiquitin carboxyl-terminal hydrolase FAM, Ubiquitin specific peptidase 9 X linked, Ubiquitin specific peptidase 9, X-linked, Ubiquitin specific processing protease FAF X, Ubiquitin specific protease 9 X chromosome, Ubiquitin thioesterase FAF X, Ubiquitin thiolesterase FAF X, Ubiquitin thiolesterase FAF-X, Ubiquitin-specific protease 9, Ubiquitin-specific-processing protease FAF-X, USP9 (gene name), Usp9x, USP9X, Uubiquitin specific protease 9, X chromosome (fat facets like Drosophila), X chromosome, X-linked,
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Application Notes
WB:1:1, 000-1:2, 000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Background
Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Specifically hydrolyzes 'Lys-48'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Essential component of TGF-beta/BMP signaling cascade. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Deubiquitinates alkylation repair enzyme ALKBH3. OTUD4 recruits USP7 and USP9X to stabilize ALKBH3, thereby promoting the repair of alkylated DNA lesions. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Involved in axonal growth and neuronal cell migration.
Manufacturer - Product
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Manufacturer - Specificity
USP9x polyclonal antibody detects endogenous levels of USP9x protein.
Molecular Weight
292 kDa
Note
For research use only, not for use in diagnostic procedure.
Immunogen
Recombinant protein within human USP9X aa 1-200.
Modification
Unmodification

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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