ArtNr |
BS91220-50 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Primary |
Applikationen |
WB, FC, IF, IHC, ICC |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
SENP1, SENP 1, SENP1, SENP1, Sentrin specific protease 1, Sentrin-specific protease 1, Sentrin/SUMO specific protease 1, Sentrin/SUMO specific protease, Sentrin/SUMO specific protease SENP 1, Sentrin/SUMO specific protease SENP1, Sentrin/SUMO-specific pro |
Lieferbar |
|
Swiss-Prot |
Q9P0U3(Human) |
Application_all |
WB:1:500-1:2, 000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100 |
Background |
Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjugates SUMO2 from MTA1. Desumoylates CCAR2 which decreases its interaction with SIRT1. Deconjugates SUMO1 from GPS2. |
Product |
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Purification And Purity |
ProA affinity purified |
Storage And Stability |
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles. |
Specificity |
SENP1 polyclonal antibody detects endogenous levels of SENP1 protein. |
BiowMW |
73 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Immunogen |
Recombinant protein within human SENP1 aa 300-500. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.