GPR218 polyclonal antibody

P62736

Actin proteins are major components of the eukaryotic cytoskeleton. At least six vertebrate actin isoforms have been identified. The cytoplasmic beta- and gamma-actin proteins are referred to as "non-muscle" actin proteins as they are predominantly expressed in non-muscle cells where they control cell structure and motility. The alpha-cardiac and alpha-skeletal actin proteins are expressed in striated cardiac and skeletal muscles, respectively. The smooth muscle alpha-actin and gamma-actin proteins are found primarily in vascular smooth muscle and enteric smooth muscle, respectively. The alpha-smooth muscle actin (ACTA2) is also known as aortic smooth muscle actin. These actin isoforms regulate the contractile potential of muscle cells.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Smooth Muscle Actin polyclonal antibody detects endogenous levels of Smooth Muscle Actin protein.

For research use only, not for use in diagnostic procedure.